General Information

A popular and medically approved weight-loss drug, Xenical (or Orlistat, as it is also commonly known) works by blocking from the body system and reducing absorption of fat from the food that is consumed. The drug contains lipstatin, which can block the effectiveness of lipase, a digestive enzyme that is produced by the pancreas.


This drug is used in addition to a low-calorie diet and exercise to help the user achieve the desired body weight. While Orlistat is available over the counter in lower dosages under the brand name Alli, Xenical can only be obtained using a doctor’s prescription as it is of a higher dosage. Xenical usually comes with a recommended dosage of one 120mg capsule three times a day along with each main meal. The drug can be consumed either during or after the meal.

Who Can it Help in Weight Loss?

Several studies have shown that Xenical is indeed an effective fat-loss and ultimately weight loss drug, with proven efficacy of helping patients lose almost 20% of their body over time. This drug is also a good choice for the maintenance of weight after weight loss. Many patients have also managed to maintain their body weight even after stopping their consumption of the drug for 1 year, this making this a very popular weight loss drug option.

What Are Some Possible Side Effects?

The use of Xenical does have some side effects that one should take note of and consider before going on a course of the drug. Firstly, as the drug has a fat-blocking property, it is common to get oily or fatty stools as well as some involuntary spotting in your undergarment. Expect some flatulence, loose stools, urgency in going to the bathroom, an inability to control bowel movements, and stomach pain, rectal pain as well as possible nausea.

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In rare cases, some extreme side effects might be experience, in which case it is recommended to stop consuming the drug and contact your doctor or visit the hospital immediately. There extreme side effects include extreme pain in your lower back, pain when urinating, the presence of blood in your urine, no urine for more than 8 hours, swelling in the feet and ankles, severe nausea, upper stomach pain, itching, fatigue, a loss of appetite or jaundice.

Contraindications to Note

Xenical is generally only available for those 18 years old and above. During the consultation with the doctor, let him or her know if you are currently suffering from liver and/or kidney disease, have any gallstones and/or kidney stones, suffer from hypothyroidism, have pancreatic, are suffering from Type 1 or Type 2 Diabetes, have an eating disorder, or if you are currently taking any other forms of medication or supplements. This can help your doctor ascertain if Xenical is safe for you.

Xenical is not for women who are pregnant as there is no conclusive study that shows how it will affect the fetus. It is also not recommended for those who have issues with their gallbladder, or suffer from a condition that prevents their ability to absorb food and nutrients in their body properly.